Studied mechanism
ERR receptors (ERRα, ERRβ, ERRγ) regulate the expression of genes involved in mitochondrial biogenesis and oxidative metabolism in skeletal muscle. SLU-PP-332 is studied as a synthetic pan-ERR agonist, with research interest focused on its ability to reproduce certain metabolic adaptations observed with physical exercise, in preclinical models.
Level of evidence
SLU-PP-332 is a recent research compound, primarily studied in animal models in the current literature. ERR mechanisms are well characterized pharmacologically, but data combining this specific compound remain at an early stage of research.
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